Berkeley Lab scientists join an international collaboration to understand how archaea and bacteria work together deep in a cold sulfur spring
In the fall of 2010, Hoi-Ying Holman of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) was approached by an international team researching a mysterious microbial community discovered deep in cold sulfur springs in southern Germany.
“They told me what they were doing and said, ‘We know what you contributed to the oil-spill research,’” recalls Holman, who heads the Chemical Ecology group in Berkeley Lab’s Earth Sciences Division. “They wondered if I could help them determine the biochemistry of their microbe samples.” (more…)
Berkeley Lab Finding that Protein Folding Funnels Also Apply to Self-Assembly Should Benefit Biomimicry and Nanosynthesis
Proteins are able to self-assemble into a wide range of highly ordered structures that feature a diverse array of properties. Through biomimicry – technological innovation inspired by nature – humans hope to emulate proteins and produce our own version of self-assembling molecules. A key to accomplishing this is understanding how protein-folding – a process critical to the form and function of a protein – is extended from individual proteins to complex assemblies.
Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have now shown that a concept widely accepted as describing the folding of a single individual protein is also applicable to the self-assembly of multiple proteins. Their findings provide important guidelines for future biomimicry efforts, particularly for device fabrication and nanoscale synthesis. (more…)
A team led by the University of Colorado Boulder looking for organisms that eke out a living in some of the most inhospitable soils on Earth has found a hardy few.
A new DNA analysis of rocky soils in the Martian-like landscape on some volcanoes in South America has revealed a handful of bacteria, fungi and other rudimentary organisms called archaea, which seem to have a different way of converting energy than their cousins elsewhere in the world.
“We haven’t formally identified or characterized the species,” said Ryan Lynch, a CU-Boulder doctoral student involved in the study. “But these are very different than anything else that has been cultured. Genetically, they’re at least 5 percent different than anything else in the DNA database of 2.5 million sequences.” (more…)
Scientists find key protein for algae growth in the ocean
Scientists have revealed a key cog in the biochemical machinery that allows marine algae at the base of the oceanic food chain to thrive. They have discovered a previously unknown protein in algae that grabs an essential but scarce nutrient out of seawater, vitamin B12.
Many algae, as well as land-dwelling animals, including humans, require B12, but they cannot make it and must either acquire it from the environment or eat food that contains B12. Only certain single-celled bacteria and archaea have the ability to synthesize B12, which is also known as cobalamin. (more…)
Researchers at the University of Hawaiʻi at Mānoa, in collaboration with scientists at the J. Craig Venter Institute, have made a significant breakthrough in developing a novel technology to investigate global gene-expression in a single bacterium. The team, led by Associate Professors Tung T. Hoang and Stuart P. Donachie, recently published a paper describing the technology in Genome Research (21:925-935), a premier international genome journal. UH Mānoa postdoctoral researcher Dr. Yun Kang, who performed this research in a Snyder Hall laboratory, contributed significantly and worked diligently to overcome the numerous technical challenges presented. (more…)
*Berkeley Lab scientists decipher immune system for plants beneath our feet*
Those vegetables you had for dinner may have once been protected by an immune system akin to the one that helps you fight disease. Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the Netherland’s Wageningen University found that plants rely on a complex community of soil microbes to defend themselves against pathogens, much the way mammals harbor a raft of microbes to avoid infections.
The scientists deciphered, for the first time, the group of microbes that enables a patch of soil to suppress a plant-killing pathogen. Previous research on the phenomenon of disease-suppressive soil had identified one or two pathogen-fighting microbes at work. (more…)
Imagine a war in which you are vastly outnumbered by an enemy that is utterly relentless – attacking you is all it does. The intro to another Terminator movie? No, just another day for microbes such as bacteria and archaea, which face a never-ending onslaught from viruses and invading strands of nucleic acid known as plasmids.
