Researchers urge appropriate use of androgen deprivation therapy
ANN ARBOR, Mich. — Men treated with hormone-based therapy for prostate cancer faced a 30 percent to 40 percent higher risk of colorectal cancer, compared to patients who did not receive this treatment, according to a new study. (more…)
A new study on gaming and health in adolescents, conducted by researchers at Yale School of Medicine, found some significant gender differences linked to gaming as well as important health risks associated with problematic gaming. Published yesterday in the journal Pediatrics, the study is among the first and largest to examine possible health links to gaming and problematic gaming in a community sample of adolescents.
Rani Desai, associate professor of psychiatry and epidemiology and public health at Yale, and colleagues anonymously surveyed 4,028 adolescents about their gaming, problems associated with gaming and other health behaviors. They found that 51.2% of the teens played video games (76.3% of boys and 29.2% of girls). The study not only revealed that, overall, there were no negative health consequences of gaming in boys, but that gaming was linked to lower odds of smoking regularly. Among girls, however, gaming was associated with getting into serious fights and carrying a weapon to school. (more…)
Image credit: University of California
Low-income neighborhoods appear to be the most susceptible to West Nile virus, a mosquito-transmitted disease that is linked to more than 1,000 deaths since in the United States since 1999, according to new UCLA-lead research.
Using data on infected humans and mosquitoes from the West Nile virus hotspot of Orange County, Calif., from 2005-08, scientists found that per-capita income and other economic conditions were the single greatest predictor of occurrence, explaining 85-95 percent of the variation. While economic conditions have previously been linked to disease, the study is the first to use a rigorous statistical model. (more…)
Study sheds light on what E. coli genes are doing inside the body during infection
E. coli bacteria. Image credit: Amy Simms, Ph.D
ANN ARBOR, Mich. — Urinary tract infections are a painful, recurring problem for millions of women. They are also getting more dangerous as bacteria develop resistance to the most common treatments.
Scientists from the University of Michigan have moved one step closer to a vaccine that could prevent a majority of urinary tract infections, which are caused by E. coli bacteria. Using a genetic technique rarely used to look at infections in human hosts, the researchers studied how the E. coli bacteria operate and discovered key differences between how the bacteria’s genes behave in women and how they behave in mice used in experiments.
Their findings, published online Nov. 11 in PLoS Pathogens, could lead to developments that would save billions in health care costs and millions of doctors’ visits and hospitalizations from urinary tract infections each year. (more…)
Image credit: University of Toronto
U of T scientists have found that chemicals used to line junk food wrappers and microwave popcorn bags are migrating into food and being ingested by people where they are contributing to chemical contamination observed in blood.
Perfluorinated carboxylic acids or PFCAs are the breakdown products of chemicals used to make non-stick and water- and stain-repellant products ranging from kitchen pans to clothing to food packaging. PFCAs, the best known of which is perfluorooctanoic acid (PFOA), are found in humans all around the world. (more…)
Mouse Stroke. An MRI of a mouse brain after stroke. The mouse section has been stained to show cell bodies. Image credit: University of California
A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone’s life forever, affecting motor activity, speech, memories, and more.
The brain makes an attempt to rally by itself, sprouting a few new connections, called axons, that reconnect some areas of the brain. But the process is weak, and the older the brain, the poorer the repair. Still, understanding the cascade of molecular events that drive even this weak attempt could lead to developing drugs to boost and accelerate this healing process.
Now researchers at UCLA have achieved a promising first step. Reporting in the current online edition of the journal Nature Neuroscience, senior author Dr. S. Thomas Carmichael, a UCLA associate professor of neurology, and colleagues have, for the first time, identified in the mouse the molecular cascade that drives the process of reconnection or sprouting in the adult brain after stroke. (more…)
COLUMBUS, Ohio – Depression appears to be associated with a molecular-level disturbance in the body’s 24-hour clock, new research suggests.
Scientists examined genes that regulate circadian rhythm in people with and without a history of depression. As a group, those with a history of depression had a higher level of activity of the so-called Clock gene, which has a role in regulating circadian rhythm, than did people with no mood disorders.
Higher expression levels of this gene suggest something is amiss in the body’s 24-hour biological and behavioral cycle, which could affect sleep patterns and other physiological functions governed by circadian rhythm. Sleep disturbance is a common symptom of depression. (more…)
New research from North Carolina State University shows that most online news stories about cancer contain language that likely contributes to public uncertainty about the disease – a significant finding, given that at least one-third of Americans seek health information online.
“Previous studies show that more than 100 million Americans seek health information online, and that their findings affect their health decisions,” says Dr. Kami Kosenko, an assistant professor of communication at NC State and co-author of a paper describing the study. “But, while people facing uncertainty about cancer issues are likely to seek out additional information, we’ve found that there are features of the information they’re seeking that may actually exacerbate the uncertainty.” (more…)
