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Research Shows a Promising New Method to Reduce Graft-Versus-Host-Disease After Bone Marrow Transplantation

By Guest PostOctober 13, 2010Health, Sciencedamon runyon cancer research foundation, global immunosuppression, graft-versus-host disease, immune attack, immune system, ivan maillard, leukemia

ANN ARBOR, Mich.—University of Michigan researchers have discovered a new method to prevent the immune-system attacks that often occur following bone marrow transplants.

Bone marrow transplantation can cure patients with leukemia and other cancers even when the disease is resistant to other treatments. The success of this procedure relies on killing cancer cells by using immune cells from a bone marrow donor while avoiding an immune attack against the patient’s organs, which causes a dangerous complication called graft-versus-host disease. (more…)

Nicotine May Play Key Role in Promising Alzheimer’s Therapy

By Guest PostOctober 13, 2010Health, Sciencea-beta, alpha7 nicotinic acetylcholine receptor, alpha7 receptor, alzheimer, angela lee, bace-1 knockouts, bace1, brain nicotine receptors, calcium uptake, disease, enzyme, fiona laird, hey kyoung lee, hui wang, lihua song, neurological disorder, neurons, neuroscientists, neurotransmitters, nicotine, normal brain function, peptide, philip c wong, schizophrenia, sixth-leading cause of death, united states, university of maryland

COLLEGE PARK, Md. — A team of neuroscientists has discovered important new information in the search for an effective treatment for Alzheimer’s disease, the debilitating neurological disorder that afflicts more than 5.3 million Americans and is the sixth-leading cause of death in the United States. Hey-Kyoung Lee , associate professor in the University of Maryland Department of Biology, and her research team have shown that they may be able to eliminate debilitating side effects caused by a promising Alzheimer’s drug by stimulating the brain’s nicotine receptors. (more…)

One Step Closer to a Drug Treatment for Cystic Fibrosis, MU Professor Says

By Guest PostOctober 13, 20101 commentHealth, Scienceatp, cell, cftr, chloride channels, cystic fibrosis, cystic fibrosis transmembrane conductance regulator, drug, fatal genetic diseases, genetic mutations, paper of the week, protein, tzyh chang hwang, university of missouri

*Study recognized for significance and importance in the world’s most common genetic disease*

COLUMBIA, Mo. – A University of Missouri researcher believes his latest work moves scientists closer to a cure for cystic fibrosis, one of the world’s most common fatal genetic diseases. (more…)

Tuberculosis Protects Itself Against Toxic Agents Sent to Destroy It

By Guest PostOctober 12, 2010Health, Sciencebacterium, cleavage function, harsh conditions, immunology, latent tuberculosis, mycobacterium tuberculosis, tapan biswas, tuberculosis, university of michigan

ANN ARBOR, Mich.—Tuberculosis fights off the toxic agents, acidity and oxidants, that our immune system sends to destroy it, which is why the maddeningly drug-resistant bacterium can survive in harsh conditions in our bodies for essentially as long as its human host lives, new research shows. (more…)

Greater Priority Should be Given to Stroke Prevention in Developing Countries

By Guest PostOctober 10, 20102 commentsHealth, Sciencebill & melinda gates foundation, chronic disease, epidemiology, global poverty reduction, peter lloyd-sherlock, prioritise preventative, stroke prevention, university of east anglia

Increased global attention and research needs to be given to stroke prevention and the social and economic effects of the condition in developing countries, according to an academic at the University of East Anglia (UEA). (more…)

UMD and UMass Chemists Design Cloaked, Anti-Cancer Toxin to Kill Tumors from Within

By Guest PostOctober 9, 20101 commentHealth, Scienceanti-cancer toxin, biomolecules, cucurbituril, gold nanoparticle, lyle isaacs, nature chemistry, supramolecular chemistry, uncloaked toxic, university of massachusetts, vincent rotello

COLLEGE PARK, Md. — A research team including University of Maryland chemistry and biochemistry Professor Lyle Isaacs and University of Massachusetts Amherst chemist Vincent Rotello has demonstrated that they can deliver a dormant toxin into a specific site such as a tumor for anti-cancer therapy, then chemically trigger the toxin to de-cloak and attack from within. It holds promise as a complex and sophisticated synthetic, therapeutic drug delivery system for living cells. (more…)

New Research Gets to the Heart of How Niacin Fights High cholesterol, Points to a New Pathway

By Guest PostOctober 8, 20101 commentHealthadult americans, apoc3, blood cholesterol, blood triglycerides, cell metabolism, fat tissues, fibrates, hdls, heart attack, heart disease, high blood lipids, jiandie lin, lipid metabolism, pgc-1beta, sirna therapeutics, united states, university of michigan, vitamin b3

ANN ARBOR, Mich.— High blood lipids are a big risk factor for developing heart disease, which is the leading cause of death in the United States. Approximately one of every six adult Americans has high blood cholesterol and about every 25 seconds, an American will have a heart attack, and nearly one every minute will die from it, according to the Centers for Disease Control and Prevention. (more…)

Cheek Swab May Detect Lung Cancer

By Guest PostOctober 6, 20101 commentHealthcancer survival rates, cheek swab, detect lung cancer, lung cancer, partial wave spectroscopic, risk stratification technique

In clinical trial, technique appears to detect lung cancer far afield from a tumor

Early detection is critical for improving cancer survival rates. Yet, one of the deadliest cancers in the United States, lung cancer, is notoriously difficult to detect in its early stages. (more…)

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