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Compound in Grapes, Red Wine Could be Key to Fighting Prostate Cancer

By Guest PostNovember 10, 2012Healthaggressive tumor, animal model, cancer, cardiovascular health, cell, chemotherapy, clinical trials, compound, granzyme b, grape skins, grocery stores, human health, michael nicholl, missouri, perforin, prostate cancer, prostate tumor, proteins, radiation therapy, radiation treatment, red wine, resveratrol, stroke prevention, therapeutic agent, university

MU researcher finds that prostate tumor cells are more susceptible to treatment after being exposed to resveratrol, a compound found in grape skins and red wine.

Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University of Missouri researcher has discovered that the compound can make prostate tumor cells more susceptible to radiation treatment, increasing the chances of a full recovery from all types of prostate cancer, including aggressive tumors.

“Other studies have noted that resveratrol made tumor cells more susceptible to chemotherapy, and we wanted to see if it had the same effect for radiation therapy,” said Michael Nicholl, an assistant professor of surgical oncology in the MU School of Medicine. “We found that when exposed to the compound, the tumor cells were more susceptible to radiation treatment, but that the effect was greater than just treating with both compounds separately.” (more…)

Gold Nanoparticle Prostate Cancer Treatment Found Safe in Dogs, MU Study Shows

New treatment may have fewer side effects than traditional cancer therapy

COLUMBIA, Mo. — Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect bodily functions. Now, scientists at the University of Missouri have proven that a new form of prostate cancer treatment that uses radioactive gold nanoparticles, and was developed at MU, is safe to use in dogs. Sandra Axiak-Bechtel, an assistant professor in oncology at the MU College of Veterinary Medicine, says that this is a big step for gold nanoparticle research.

“Proving that gold nanoparticles are safe to use in the treatment of prostate cancer in dogs is a big step toward gaining approval for clinical trials in men,” Axiak-Bechtel said. “Dogs develop prostate cancer naturally in a very similar way as humans, so the gold nanoparticle treatment has a great chance to translate well to human patients.” (more…)

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Compound in Grapes, Red Wine Could be Key to Fighting Prostate Cancer

Gold Nanoparticle Prostate Cancer Treatment Found Safe in Dogs, MU Study Shows