ANN ARBOR — What started as a politically liberal Facebook meme in support of health care reform morphed as it spread across the social network into hundreds of thousands of variations—some just a few words from the original, but others centered on taxes, beer, or Star Wars’ villain Jabba the Hutt.
The twists on the original text over time in many ways mirrored the evolution of biological genes, researchers from the University of Michigan and Facebook have found. (more…)
AMHERST, Mass. – Launching a natural research experiment in Kathmandu, Nepal, this month using advanced monitoring methods to assess health risk from air pollution, environmental health scientist Rick Peltier at the University of Massachusetts Amherst hopes to demonstrate for the first time in a real-world setting that air pollution can and should be regulated based on toxicology variables rather than simply on the volume of particles in the air.
Recent technological advances in air quality measurement methods now make it possible and practical to monitor air pollution in a much more sophisticated way than before, Peltier says. Researchers now use X-ray fluorescence spectrometry to measure air pollution metal content, ion chromatography to identify other chemicals and other tactics to assess organic and elemental carbon levels. (more…)
Mice and monkeys don’t develop diseases in the same way that humans do. Nevertheless, after medical researchers have studied human cells in a Petri dish, they have little choice but to move on to study mice and primates.
University of Washington bioengineers have developed the first structure to grow small human blood vessels, creating a 3-D test bed that offers a better way to study disease, test drugs and perhaps someday grow human tissues for transplant.
*Researchers have created a living 3-D model of a brain tumor and its surrounding blood vessels. In experiments, the scientists report that iron-oxide nanoparticles carrying the agent tumstatin were taken by blood vessels, meaning they should block blood vessel growth. The living-tissue model could be used to test the effectiveness of nanoparticles in fighting other diseases. Results appear in Theranostics.*
PROVIDENCE, R.I. [Brown University] — Brown University scientists have created the first three-dimensional living tissue model, complete with surrounding blood vessels, to analyze the effectiveness of therapeutics to combat brain tumors. The 3-D model gives medical researchers more and better information than Petri dish tissue cultures.
The researchers created a glioma, or brain tumor, and the network of blood vessels that surrounds it. In a series of experiments, the team showed that iron-oxide nanoparticles ferrying the chemical tumstatin penetrated the blood vessels that sustain the tumor with oxygen and nutrients. The iron-oxide nanoparticles are important, because they are readily taken up by endothelial cells and can be tracked by magnetic resonance imaging. (more…)
