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Cannibal Tadpoles Key to Understanding Digestive Evolution

By Guest PostMay 25, 2013Scienceafrican clawed frog, anne everly, budgetts frog, cannibal tadpoles, carlos infante, carnivorous, cris ledon rettig, digestive evolution, function, human birth defects, intestinal birth defects, james hanken, lepidobatrachus laevis, molecules, nanette nascone yoder, north Carolina, proteins, state university, tadpole, xenopus, xenopus embryos, xenopus laevis

A carnivorous, cannibalistic tadpole may play a role in understanding the evolution and development of digestive organs, according to research from North Carolina State University. These findings may also shed light on universal rules of organ development that could lead to better diagnosis and prevention of intestinal birth defects.

NC State developmental biologist Nanette Nascone-Yoder, graduate student Stephanie Bloom and postdoc Cris Ledon-Rettig looked at Xenopus laevis (African clawed frog) and Lepidobatrachus laevis (Budgett’s frog) tadpoles. These frog species differ in diet and last shared a common ancestor about 110 million years ago. Like most tadpoles, Xenopus exist primarily on a diet of algae, and their long, simple digestive tracts are not able to process insects or proteins until they become adult frogs. Budgett’s is an aggressive species of frog which is carnivorous – and cannibalistic – in the tadpole stage. (more…)

Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time

By Guest PostMay 20, 2013Sciencealginate, blood sugar, blood sugar levels, bloodstream, chitosan, closed loop system, daniel anderson, dextran, diabetes patients, diabetes treatment, gluconic acid, glucose, glucose oxidase enzymes, hormone, injectable nano network, injection, insulin, massachusetts institute, material, nanoparticle cores, nanoscale particles, network, north Carolina, robert langer, seaweed, shrimp shells, state university, Technology, type 1 diabetes, unc chapel, zhen gu

In a promising development for diabetes treatment, researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise, maintaining normal blood sugar levels for more than a week in animal-based laboratory tests. The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children’s Hospital Boston.

“We’ve created a ‘smart’ system that is injected into the body and responds to changes in blood sugar by releasing insulin, effectively controlling blood-sugar levels,” says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at NC State and UNC Chapel Hill. “We’ve tested the technology in mice, and one injection was able to maintain blood sugar levels in the normal range for up to 10 days.” (more…)

Paper Offers Framework for Amazon Oil and Gas Development

By Guest PostMay 12, 2013Environment, Generalamazonian hydrocarbon exploration, amazonian region, analysis, bill powers, blue moon fund, clinton jenkins, critical ecosystems, cultural diversity, dynamic hydrocarbon zones, earth, emergency, environmental state, erd, etech international, extended reach drilling, future conflicts, gas, key component, matt finer, national geographic society, negative impact, north Carolina, northern peru, oil, production, state university, technique, tropical forest environment, vital watersheds, western amazon

Oil and gas development continues to press into the most remote corners of the western Amazon, one of the most biologically and culturally diverse zones on Earth. Now a study proposes a new 10-point, best-practice framework that combines technical engineering criteria with consideration of ecological and social concerns to reduce the negative impacts of Amazonian hydrocarbon exploration and production.

The researchers say, for example, that by using extended reach drilling (ERD), a technique to reach a larger subsurface area from one surface drilling location, it is possible to greatly reduce the total number of needed drilling platforms and access roads for a given project. (more…)

Older Is Wiser: Study Shows Software Developers’ Skills Improve Over Time

By Guest PostMay 9, 2013Technologychanging technology, data, django to silverlight, emerson murphy hill, ios, north Carolina, older is wiser, patrick morrison, programming interests, programming issues, reputation score, skills of programmers, smartphone operating systems, software developer, stackoverflow, state university, windows phone

There is a perception in some tech circles that older programmers aren’t able to keep pace with rapidly changing technology, and that they are discriminated against in the software field. But a new study from North Carolina State University indicates that the knowledge and skills of programmers actually improve over time – and that older programmers know as much (or more) than their younger peers when it comes to recent software platforms.

“We wanted to explore these perceptions of veteran programmers as being out of step with emerging technologies and see if we could determine whether older programmers are actually keeping up with changes in the field,” says Dr. Emerson Murphy-Hill, an assistant professor of computer science at NC State and co-author of a paper on the research. “And we found that, in some cases, veteran programmers even have a slight edge.” (more…)

New Algorithm Helps Evaluate, Rank Scientific Literature

By Guest PostMay 5, 2013Scienceallan peter davis, biocurators, bioinformatician, carolyn mattingly, cindy murphy, code, computer program, ctd, evaluate, jean lay, new algorithm, north Carolina, public database, rank, robin johnson, scientific literature, sophisticated algorithm, state university, thomas wiegers

Keeping up with current scientific literature is a daunting task, considering that hundreds to thousands of papers are published each day. Now researchers from North Carolina State University have developed a computer program to help them evaluate and rank scientific articles in their field.

The researchers use a text-mining algorithm to prioritize research papers to read and include in their Comparative Toxicogenomics Database (CTD), a public database that manually curates and codes data from the scientific literature describing how environmental chemicals interact with genes to affect human health. (more…)

Research Finds Invasive Kudzu Bugs May Pose Greater Threat Than Previously Thought

By Guest PostApril 29, 2013Natureagricultural pest, alejandro, asia, crop damage, del pozo valdivia, dominic reisig, entomology, generation a, georgia, invasive kudzu bug, megacopta cribraria, nc state, north Carolina, soybean crops, state university, united states, virginia

The invasive kudzu bug has the potential to be a major agricultural pest, causing significant damage to economically important soybean crops. Conventional wisdom has held that the insect pests will be limited to areas in the southern United States, but new research from North Carolina State University shows that they may be able to expand into other parts of the country.

Kudzu bugs (Megacopta cribraria) are native to Asia, and were first detected in the U.S. in Georgia in 2009. They have since expanded their territory as far north as Virginia. The bugs have an interesting life cycle, which has been thought to be a limiting factor on far they can spread. (more…)

Foundations of Carbon-Based Life Leave Little Room for Error

By Guest PostApril 2, 2013Sciencealpha particles, carbon, carbon 12, carbon based life, dean lee, deutsche forschungsgemeinschaft, electron volts, elementary particles, elements, evgeny epelbaum, helium 4 nuclei, hermann krebs, hoyle state, juelich supercomputer centre, kev, light quark mass, north Carolina, numerical lattice, oxygen, quarks, room for error, specific energy, state university, timo laehde, ulf g

Life as we know it is based upon the elements of carbon and oxygen. Now a team of physicists, including one from North Carolina State University, is looking at the conditions necessary to the formation of those two elements in the universe. They’ve found that when it comes to supporting life, the universe leaves very little margin for error.

Both carbon and oxygen are produced when helium burns inside of giant red stars. Carbon-12, an essential element we’re all made of, can only form when three alpha particles, or helium-4 nuclei, combine in a very specific way. The key to formation is an excited state of carbon-12 known as the Hoyle state, and it has a very specific energy – measured at 379 keV (or 379,000 electron volts) above the energy of three alpha particles. Oxygen is produced by the combination of another alpha particle and carbon. (more…)

New Technique Creates Stronger, Lightweight Magnesium Alloys

By Guest PostMarch 29, 2013Scienceaerospace industries, automobile, conventional, gadolinium, hot rolling technology, lightweight magnesium alloys, nano spaced, nc state, new technique, north Carolina, silver, specific strength, stacking faults, state university, suveen mathaudhu, us army research, yttrium, yuntian zhu, zirconium

Researchers from North Carolina State University have developed a new technique for creating stronger, lightweight magnesium alloys that have potential structural applications in the automobile and aerospace industries.

Engineers constantly seek strong, lightweight materials for use in cars and planes to improve fuel efficiency. Their goal is to develop structural materials with a high “specific strength,” which is defined as a material’s strength divided by its density. In other words, specific strength measures how much load it can carry per unit of weight. (more…)

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