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Previous Studies on Toxic Effects of BPA Couldn’t be Reproduced, says MU Research Team

By Guest PostJanuary 9, 2013Environmentagouti, agouti signaling protein, animal numbers, asip, bpa, cheryl rosenfeld, controversial chemical, dietary supplement, equal ratios, estrogenic compound, exposure, famine, fat tissue, frederick vomsaal, gene, genistein, humans, metabolic disorders, mice, obesity, obesity related disease, offspring, pancreas, plants, plastic bottles, replicate, reproduce, soy beans, thrifty genotype, type 2 diabetes, university of missouri, uterine environments, womb, yellow coat color

The MU study is not claiming that BPA is safe, but that the previous series of studies are not reproducible.

COLUMBIA, Mo. — Following a three-year study using more than 2,800 mice, a University of Missouri researcher was not able to replicate a series of previous studies by another research group investigating the controversial chemical BPA. The MU study is not claiming that BPA is safe, but that the previous series of studies are not reproducible. The MU study, published in the Proceedings of the National Academy of Sciences, also investigated an estrogenic compound found in plants, genistein, in the same three-year study.

“Our findings don’t say anything about the positive or negative effects of BPA or genistein,” said Cheryl Rosenfeld, associate professor of biomedical sciences in MU’s Bond Life Science Center. “Rather, our series of experiments did not detect the same findings as reported by another group on the potential developmental effects of BPA and genistein when exposure of young occurs in the womb.” (more…)

Obesity: Yale Researcher Explains Why It’s All in Our Heads

Tamas Horvath. Image credit: Yale University

Tamas Horvath is the first to tell you that he doesn’t study obesity. But his research on the effects of metabolism on higher brain functions could provide deeper understanding of the brain’s link to appetite, weight and to metabolic disorders such as diabetes and obesity.

His lab was the first to provide evidence that the brain uses fat as fuel. Horvath has also studied how endocrine signals in the brain regulate neurodegenerative diseases such as Parkinson’s and Alzheimer’s.

Horvath followed his father and grandfather into veterinary medicine in his native Hungary, but his training sparked a passion for basic research. His achievements have earned him a long title that speaks to his varied research interests. He became chair of the Department of Comparative Medicine at Yale School of Medicine in 2005, and he is also a professor in the Departments of Obstetrics, Gynecology & Reproductive Sciences and Neurobiology. Horvath also heads the Program on Integrative Cell Signaling and the Neurobiology of Metabolism. (more…)

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Previous Studies on Toxic Effects of BPA Couldn’t be Reproduced, says MU Research Team

Obesity: Yale Researcher Explains Why It’s All in Our Heads