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How Silver Turns People Blue

By Guest PostOctober 27, 2012Scienceabsorb, acidic environment, agnes kane, antimicrobial, argyria, base membrane, bioavailable salt, bloodstream, brown researcher, brown university, charged ions, disorder, electron, environmental impact, exposure scenario, frances liu, germs, gi tract, grayish blue, health tonics, jingyu liu, medical treatment, nanoparticle, particle, photochemical reaction, protein, robert hurt, salt ion, silver, silver atom, silver salt, skin, toxic, toxicity, zhongying wang

Ingesting silver — in antimicrobial health tonics or for extensive medical treatments involving silver — can cause argyria, condition in which the skin turns grayish-blue. Brown researchers have discovered how that happens. The process is similar to developing black-and-white photographs, and it’s not just the silver.

PROVIDENCE, R.I. [Brown University] — Researchers from Brown University have shown for the first time how ingesting too much silver can cause argyria, a rare condition in which patients’ skin turns a striking shade of grayish blue.

“It’s the first conceptual model giving the whole picture of how one develops this condition,” said Robert Hurt, professor of engineering at Brown and part of the research team. “What’s interesting here is that the particles someone ingests aren’t the particles that ultimately cause the disorder.” (more…)

Why Bad Immunity Genes Survive

By Guest PostFebruary 10, 2012Health, Scienceankylosing spondylitis, antagonistic co evolution, antibiotics, arms race, autoimmune diseases, bacteria, cells, cornelius whitney hyzer, gene, genetics, george gilchrist, germs, immune system, infection, infectious diseases, james ruff, jason kubinak, major histocompatibility complex, mhc, mhc variants, mhcs, mice, national science foundation, parasite, pathogens, patricia slev, people, protein, university of utah, variant, vertebrate animals, virus, wayne potts

*Study implicates “arms race” between genes and germs*

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs–even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

“Major histocompatibility complex” (MHC) proteins are found on the surfaces of most cells in vertebrate animals. They distinguish proteins like themselves from foreign proteins, and trigger an immune response against these foreign invaders. (more…)

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How Silver Turns People Blue

Why Bad Immunity Genes Survive