Berkeley Lab scientist Ee-Been Goh thrives on re-engineering bacteria and mentoring students.
To see biochemist Ee-Been Goh in the lab today, figuring out how to rewire bacteria to produce biofuels, one would never guess she was once so uninterested in school that she barely made it through junior high. (more…)
Berkeley Researchers Show Expanded Role for Guide RNA in Cas9 Interactions with DNA
The potential is there for bacteria and other microbes to be genetically engineered to perform a cornucopia of valuable goods and services, from the production of safer, more effective medicines and clean, green, sustainable fuels, to the clean-up and restoration of our air, water and land. Cells from eukaryotic organisms can also be modified for research or to fight disease. To achieve these and other worthy goals, the ability to precisely edit the instructions contained within a target’s genome is a must. A powerful new tool for genome editing and gene regulation has emerged in the form of a family of enzymes known as Cas9, which plays a critical role in the bacterial immune system. Cas9 should become an even more valuable tool with the creation of the first detailed picture of its three-dimensional shape by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley. (more…)
Enzymes evolved in the lab hold commercial and scientific promise
Whether big, small, slimy, or tall, most animal bodies are symmetric.
Except for sea anemones, starfish, sponges, and the like, animals have bilateral, or right-left, symmetry. Us included.
The bilateral body plan became the norm over eons of evolution. But what about molecules? Have any evolved common structures like a body plan? (more…)
