Technology

Computer models figure out sickle cell crisis

A sickle cell crisis isn’t just about sickle-shaped red blood cells that block capillaries. A second, stickier kind of red blood cell starts the obstruction, making it difficult for sickle cells to flow past.

PROVIDENCE, R.I. [Brown University] — Using powerful computer models, researchers from Brown University have shown for the first time how different types of red blood cells interact to cause sickle cell crisis, a dangerous blockage of blood flow in capillaries that causes searing pain and tissue damage in people with sickle cell disease.

The models showed that the rigid, crescent-shaped red blood cells that are the hallmark of sickle cell disease don’t cause these blockages on their own. Instead, softer, deformable red blood cells known as SS2 cells start the process by sticking to capillary walls. The rigid sickle-shaped cells then stack up behind the SS2s, like traffic behind a car wreck. (more…)

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Dr. Mark Michalski is ready to print a 3-D brain (maybe yours)

In a year’s time, the 3-D printers at Yale’s Center for Engineering Innovation and Design (CEID) have churned out countless parts, prototypes, and curiosity-driven experiments in plastic — rotorheads and racecar uprights, cardiac pump pieces and thermostats, snowmen, keychains, and fantastical geometric shapes. (more…)

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Black Bears Return to Missouri Indicates Healthy Forests, say MU Biologists

Outdoor recreationists should take precautions to avoid problems with bears in southern Missouri

COLUMBIA, Mo. — For nearly a century, the only bears known to reside in Missouri were on the state flag or in captivity. Unregulated hunting and habitat loss had wiped out most black bears in Missouri, Arkansas and Oklahoma by the 1920s. Now, thanks to a reintroduction program in Arkansas during the 50s and 60s, hundreds of bears amble through the forests of southern Missouri, according to a joint study by University of Missouri, Mississippi State University, and Missouri Department of Conservation biologists, who warn that although the bear population is still small, outdoor recreationists and homeowners should take precautions in the Ozark forest to avoid attracting bears.

“Black bears normally do not attack humans, but they will ransack picnic baskets, tear through garbage bags or even enter buildings looking for food,” said Lori Eggert, associate professor of biological sciences in MU’s College of Arts and Science. “Although some Missourians may be concerned, the return of black bears to Missouri is actually a good sign. It means parts of the state’s forests are returning to a healthy biological balance after nearly two centuries of intensive logging and exploitation.” (more…)

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China’s chance to reinvent itself environmentally

China’s 34-year-old Environmental Protection Law was created when it made sense for legislators in a developing country to trade environmental well-being for a boost to the gross domestic product.

Today, China wrestles with pollution that is leaving its citizens gasping for clean air, worried about water quality and concerned for the safety of the food grown there. In the current issue of Science, a team of researchers, including a Michigan State University sustainability expert, offers guidelines for revising the EPL to protect both humans and nature. (more…)

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Scientists Discover Thriving Colonies of Microbes in Ocean ‘Plastisphere’

Scientists have discovered a diverse multitude of microbes colonizing and thriving on flecks of plastic that have polluted the oceans—a vast new human-made flotilla of microbial communities that they have dubbed the “plastisphere.”

In a study recently published online in Environmental Science & Technology, the scientists say the plastisphere represents a novel ecological habitat in the ocean and raises a host of questions: How will it change environmental conditions for marine microbes, favoring some that compete with others? How will it change the overall ocean ecosystem and affect larger organisms? How will it change where microbes, including pathogens, will be transported in the ocean? (more…)

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How the brain creates the ‘buzz’ that helps ideas spread

How do ideas spread? What messages will go viral on social media, and can this be predicted?

UCLA psychologists have taken a significant step toward answering these questions, identifying for the first time the brain regions associated with the successful spread of ideas, often called “buzz.”

The research has a broad range of implications, the study authors say, and could lead to more effective public health campaigns, more persuasive advertisements and better ways for teachers to communicate with students. (more…)

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