Tag Archives: protein structure

New protein structure could help treat Alzheimer’s, related diseases

There is no cure for Alzheimer’s disease and other forms of dementia, but the research community is one step closer to finding treatment.

University of Washington bioengineers have designed a peptide structure that can stop the harmful changes of the body’s normal proteins into a state that’s linked to widespread diseases such as Alzheimer’s, Parkinson’s, heart disease, Type 2 diabetes and Lou Gehrig’s disease. The synthetic molecule blocks these proteins as they shift from their normal state into an abnormally folded form by targeting a toxic intermediate phase. (more…)

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Good Vibrations: Mediating Mood Through Brain Ultrasound

Ultrasound vibrations applied to the brain may affect mood, UA researchers have discovered. The finding potentially could lead to new treatments for psychological and psychiatric disorders.

University of Arizona researchers have found in a recent study that ultrasound waves applied to specific areas of the brain appear able to alter patients’ moods. The discovery has led the scientists to conduct further investigations with the hope that this technique could one day be used to treat conditions such as depression and anxiety.

Dr. Stuart Hameroff, professor emeritus of the UA’s departments of anesthesiology and psychology and director of the UA’s Center for Consciousness Studies, is lead author on the first clinical study of brain ultrasound, which was published in the journal Brain Stimulation. (more…)

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Revealing the Secrets of Motility in Archaea

Scientists from Berkeley Lab and the Max Planck Institute for Terrestrial Microbiology analyze a unique microbial motor

The protein structure of the motor that propels archaea has been characterized for the first time by a team of scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and Germany’s Max Planck Institute (MPI) for Terrestrial Microbiology.

The motility structure of this third domain of life has long been called a flagellum, a whip-like filament that, like the well-studied bacterial flagellum, rotates like a propeller. But although the archaeal structure has a similar function, it is so profoundly different in structure, genetics, and evolution that the researchers argue it deserves its own name: archaellum. (more…)

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