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Brighter, Smaller Probes to Uncover the Secret Lives of Proteins

By Guest PostMay 10, 20121 commentSciencealexis ostrowski, andrew mueller, berkeley lab, bruce cohen, cellular mechanism, daniel gargas, delia milliron, disease, elan katz, emory chan, erbium, function, gang han, imagine tracking, james schuck, lanthanide, live cell, los angeles, molecule, nanocrystal, nanoparticle, nayf4, photobleach, protein, radio transmitter, sodium yttrium fluoride, vistamar school, wanda robot, ytterbium

Berkeley Lab scientists create nanoparticle probes that may lead to a better understanding of diseases

Imagine tracking a deer through a forest by clipping a radio transmitter to its ear and monitoring the deer’s location remotely. Now imagine that transmitter is the size of a house, and you understand the problem researchers may encounter when they try to use nanoparticles to track proteins in live cells.

Understanding how a protein moves around a cell helps researchers understand the protein’s function and the cellular mechanisms for making and processing proteins. This information also helps researchers study disease, which at a cellular level may mean that a protein is malfunctioning, stops being made, or is sent to the wrong part of the cell. But nanoparticle probes that are too big can disrupt a protein’s normal activities. (more…)

Golden Potential for Gold Thin Films

By Guest PostApril 29, 2012Science1d chain, 2d nanoparticle, 2d sheet, berkeley lab, block, catalysis, co polymer, DNA, gold nanoparticle, joseph kao, microdomain, microtechnology, nanometer, nanoparticle, peter bai, peter ercius, plasmonic metamaterial, plasmonic technology, polymer scientist, polymer supramolecule, scalable nanomanufacturing, semiconductor nanocrystal, solvent evaporation, supramolecular nanocomposites, thin film, three dimensional array, ting xu, uc, university of california, vivian chuang, zhang jiang

Berkeley Lab Researchers Direct the Self-Assembly of Gold Nanoparticles into Device-Ready Thin films

Scientists with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have directed the first self-assembly of nanoparticles into device-ready materials. Through a relatively easy and inexpensive technique based on blending nanoparticles with block co-polymer supramolecules, the researchers produced multiple-layers of thin films from highly ordered one-, two- and three-dimensional arrays of gold nanoparticles. Thin films such as these have potential applications for a wide range of fields, including computer memory storage, energy harvesting, energy storage, remote-sensing, catalysis, light management and the emerging new field of plasmonics.

“We’ve demonstrated a simple yet versatile supramolecular approach to control the 3-D spatial organization of nanoparticles with single particle precision over macroscopic distances in thin films,” says polymer scientist Ting Xu, who led this research. “While the thin gold films we made were wafer-sized, the technique can easily produce much larger films, and it can be used on nanoparticles of many other materials besides gold.” (more…)

From Cancer Research to Energy Storage, Berkeley Lab Scientist Takes on Big Challenges

By Guest PostFebruary 3, 2012Scienceclean energy, CO2, energy, Environment, fossil fuel, hydrogen storage system, India, intel corporation, liquefied hydrogen, magnesium metal, metal hydride, molecular foundry, nanoparticle, optical spectroscopy, phase transition, plasmonic structures, rising star, rizia bardhan, Science, volumetric density

*Rizia Bardhan, a postdoc at the Molecular Foundry, selected to Forbes’ ’30 under 30′ list*

On a typical day, Rizia Bardhan walks through the doors of Lawrence Berkeley National Laboratory’s Molecular Foundry and immerses herself in the tricky business of tweaking optical spectroscopy equipment to study phase transitions in metal hydrides.

It’s fair to say that what she does is difficult to grasp. Why she does it is easy: “I want to help solve big problems. That’s why I’m here,” she says. (more…)

Novel Nanoparticle Mimicking Virus Offers New Route to Gene Therapy

By Guest PostDecember 10, 2011Sciencebrain tumors, cancer, caroline e weller, christopher j cheng, cystic fibrosis, diseases, gene therapy, healthy cells, huntingtons disease, hydrophobic, immune reactions, materials, mouse tumor model, nanoparticle, non viral gene therapy, novel chemistry, polymers, positive electric charge, repair, symptoms, treatments, viral gene therapy, w mark saltzman, water molecules, water repellant, yale university, zhaozhong jiang

Researchers at Yale University have developed a novel nanoparticle with promising applications in gene therapy, a type of medical treatment that addresses the root causes of diseases now typically treated for symptoms.

The advance could lead to new therapies for many forms of cancer, including brain tumors, as well as for cystic fibrosis and Huntington’s Disease. (more…)

Study Finds Public Relatively Unconcerned About Nanotechnology Risks

By Guest PostApril 12, 20111 commentHealth, Sciencealcohol, andrew binder, blood transfusions, cell phone use, commercial air travel, david berube, environmental and health safety risks, general public, hazardous, medical x-rays, nanoparticle, Nanotechnology, nuclear energy, obesity, public health risk, smoking, suntan

A new study finds that the general public thinks getting a suntan poses a greater public health risk than nanotechnology or other nanoparticle applications. The study, from North Carolina State University, compared survey respondents’ perceived risk of nanoparticles with 23 other public-health risks.

The study is the first to compare the public’s perception of the risks associated with nanoparticles to other environmental and health safety risks. Researchers found that nanoparticles are perceived as being a relatively low risk. (more…)

Tag Archives: nanoparticle

Brighter, Smaller Probes to Uncover the Secret Lives of Proteins

Golden Potential for Gold Thin Films

From Cancer Research to Energy Storage, Berkeley Lab Scientist Takes on Big Challenges

Novel Nanoparticle Mimicking Virus Offers New Route to Gene Therapy

Study Finds Public Relatively Unconcerned About Nanotechnology Risks