Tag Archives: laboratory

Bright Future for Protein Nanoprobes

By Guest PostMay 2, 2014Sciencealexis ostrowski, berkeley lab, biology, brighter future, bruce cohen, building blocks, daniel gargas, doe, elektronische fussfessel, emory chan, erbium, fluorescent, free asymmetric, future, gewaltdelikte, heterocontact, james schuck, joerg kinzig, laboratory, mexican men, mexico murder rate, molecular foundry, nanocrystals, photobleach, polly myer, single molecules, sodium yttrium fluoride, ytterbium

Berkeley Lab Researchers Discover New Rules for Single-Particle Imaging with Light-Emitting Nanocrystals

The term a “brighter future” might be a cliché, but in the case of ultra-small probes for lighting up individual proteins, it is now most appropriate. Researchers at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have discovered surprising new rules for creating ultra-bright light-emitting crystals that are less than 10 nanometers in diameter. These ultra-tiny but ultra-bright nanoprobes should be a big asset for biological imaging, especially deep-tissue optical imaging of neurons in the brain.

Working at the Molecular Foundry, a DOE national nanoscience center hosted at Berkeley Lab, a multidisciplinary team of researchers led by James Schuck and Bruce Cohen, both with Berkeley Lab’s Materials Sciences Division, used advanced single-particle characterization and theoretical modeling to study what are known as “upconverting nanoparticles” or UCNPs. Upconversion is the process by which a molecule absorbs two or more photons at a lower energy and emits them at higher energies. The research team determined that the rules governing the design of UCNP probes for ensembles of molecules do not apply to UCNP probes designed for single-molecules. (more…)

Scientists “Burst” Supercomputing Record with Bubble Collapse Simulation; Could Lead to Advances in Healthcare and Industrial Technology

By Guest PostNovember 18, 2013Technologyalessandro curioni, bubble collapse simulation, burst, cloud cavitation collapse, complex phenomena, engineering problems, eth zurich, fastest supercomputer, finite volume method, gordon bell prize, healthcare, ibm, ibm bluegene q, industrial technology, laboratory, llnl, petros koumoutsakos, scientist, sequoia, supercomputing record, swiss university, ultra scalable code, world

– 15,000 bubbles are simulated using IBM BlueGene/Q “Sequoia” at 14.4 Petaflop of sustained performance, a 150-fold improvement over current state-of-the-art
– Destructive capabilities of collapsing bubbles are increasingly being studied in areas ranging from treating kidney stones and cancer to high pressure fuel injectors
– Research team named as a Finalist for the 2013 Gordon Bell Prize (more…)

UCLA Relies on Breakthrough ‘Big Data’ Technology from IBM To Help Patients with Traumatic Brain Injuries

By Guest PostMarch 26, 2013Technologybrain damage, brain injury research, death, department of neurosurgery, eme, excel medical electronics, hospitals in america, ibm, ibm research, ibm software, laboratory, martin kohn, patients, rising brain pressure, spinal cord, t j watson, traumatic brain injury, ucla

Bedside Early-Warning System from IBM and Excel Medical Electronics Can Analyze Large Amounts of Data in Real Time to Predict Dangerous Changes in a Patient’s Condition

Armonk, N.Y. and Los Angeles, CA – 26 Mar 2013: IBM, and Excel Medical Electronics (EME) are collaborating with the UCLA Department of Neurosurgery in a study to test the effectiveness of a real-time alarm intended to predict rising brain pressure in patients with traumatic brain injuries. The experimental system uses big data analytics software developed by IBM Research and EME that analyzes in real-time streams of vital signs continuously collected from the bedside monitor to spot subtle changes in the patient’s pulse, blood and intracranial pressure, heart activity, and respiration, signaling that dangerous high-risk increases in brain pressure are on the way. (more…)

NASA Maps How Nutrients Affect Plant Productivity

By Guest PostNovember 3, 2012Environmentamazonia, biogeochemical cycles, boreal, boreal forest, carbon cycle, carbon dioxide, data, earth, ecosystem, eleanor blyth, eurasian forest, fertile earth, fertilization, global, grasslands, grayson badgley, greenhouse gas, growth, hawaii, jet propulsion, josh fisher, laboratory, level, maps, migration, model, NASA, nitrogen, North America, north american, nutrient, ozone mapping, palo alto, pasadena, phosphorus, plant, satellite, savannas, shrublands, soil, spectrometer, stanford university, terra spacecraft, terrestrial biosphere, total, trees, tropical forest, validation site, vegetation, vegetation productivity

PASADENA, Calif. – A new analysis led by NASA’s Jet Propulsion Laboratory, Pasadena, Calif., has estimated how much the growth of plants worldwide is limited by the amount of nutrients available in their soil. The maps produced from the research will be particularly useful in evaluating how much carbon dioxide Earth’s ecosystems may be able to soak up as greenhouse gas levels increase.

A research team led by JPL research scientist Josh Fisher used 19 years of data from NASA, National Oceanic and Atmospheric Administration and international satellites to assess the maximum possible growth of vegetation all over the world based upon available water and light conditions. The scientists then cross-compared that potential maximum with observed vegetation productivity as measured by satellites. This is the first time such an analysis has been conducted. (more…)

UCLA Researchers Map Damaged Connections in Phineas Gage’s Brain

By Guest PostMay 18, 2012Science1848 case, alzheimer's disease, andrei irimia, arthur w toga, behavioral change, brain, brain disorder, carinna m torgerson, cerebral cortex, computed tomographic data, emotional function, famous case, frontal temporal dementia, gage skull, history, human connectome project, jack van horn, laboratory, limbic structure, loni, mark wheeler, micah c chambers, microscopic links, model, myelin sheath, nerve fibers, neuro imaging, neurons, neuroscience, phineas gage, railroad, rod, san francisco, skull, south america, trajectory, traumatic brain injury, vermont, white matter

Famous 1848 case of man who survived a terrible accident has modern parallel

Poor Phineas Gage. In 1848, the supervisor for the Rutland and Burlington Railroad in Vermont was using a 13-pound, 3-foot-7-inch rod to pack blasting powder into a rock when he triggered an explosion that drove the rod through his left cheek and out of the top of his head. As reported at the time, the rod was later found, “smeared with blood and brains.”

Miraculously, Gage lived, becoming the most famous case in the history of neuroscience — not only because he survived a horrific accident that led to the destruction of much of his left frontal lobe but also because of the injury’s reported effects on his personality and behavior, which were said to be profound. Gage went from being an affable 25-year-old to one that was fitful, irreverent and profane. His friends and acquaintances said he was “no longer Gage.” (more…)

Monogamous Birds….Peeping on the Neighbours!

By Guest PostJanuary 28, 2012Naturecolourful plumage, courtship dance, disease, dominique drullion, female, female zebra finche, frederique dubois, hypothesis, immunosuppressive effect, laboratory, male bird, male genetic quality, monogamous species, public information, reproduction period, sexual selection, social environment, song, testosterone, zebra finch

It is well documented that male birds seduce females using their songs, colourful plumage and courtship dances. These signals reflect male genetic quality and will be graded by the female to determine a male’s potential as a mate. The stronger the grade, the better the odds of being selected.

But this basic rule isn’t the only yardstick used by females. As surprising as it seems, birds know how to use data from their social environment to maximize their chances of reproduction. Frédérique Dubois, a professor at the Université de Montréal Department of Biological Sciences, has already demonstrated that female Zebra Finches will favour a male chosen by another female. Dubois refers to this as imitation and the use of “public information” in choosing a mate. (more…)

Who’s More Likely to offer a Bribe?

By Guest PostOctober 8, 2011Culturebribery, business person, collective feeling, collectivist cultures, corruption, kurt kleiner, laboratory, nina mazar, pankaj aggarwal, researchers, society, university of toronto scarborough, utsc

*U of T professors show collectivism and bribery linked*

Why are some places more prone to bribery and corruption than others?

Part of the answer seems to be the level of collective feeling in a society, according to research by Pankaj Aggarwal, University of Toronto Scarborough (UTSC) professor of marketing in the Department of Management, and Nina Mazar, University of Toronto professor of marketing. (more…)

Improved Measurements of Sun to Advance Understanding of Climate Change

By Guest PostJanuary 17, 2011Environment, Scienceamount of energy, anthropogenic causes of climate change, calibration facility, climate change, climate respond, earth, global temperature, global warming, greg kopp, industrial revolution, judith lean, laboratory, NASA, optical design, planet, satellite data, solar fluctuations, solar irradiance, solar radiation and climate experiment spacecraft, sorce, spacecraft easurements, sun, tim, total irradiance monitor, total solar irradiance, tsi, tsi value

WASHINGTON — Scientists have taken a major step toward accurately determining the amount of energy that the sun provides to Earth, and how variations in that energy may contribute to climate change.

In a new study of laboratory and satellite data, researchers report a lower value of that energy, known as total solar irradiance, than previously measured and demonstrate that the satellite instrument that made the measurement—which has a new optical design and was calibrated in a new way—has significantly improved the accuracy and consistency of such measurements. (more…)