A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus’ genetic material. The findings from the University of Chicago and the Massachusetts Institute of Technology could bolster efforts to develop the next generation of anti-viral treatments. (more…)
Yale University researchers have identified four unique host defense proteins among thousands that seem to play a crucial role in mobilizing the immune system’s response to bacterial infections, they report in the May 6 issue of the journal Science.
The findings suggest it may be possible to find new ways to assist immune-compromised patients to fight off a variety of pathogens, the authors say.
“We can start to think about how to mimic these chemical processes and deliver them in drug form,” said John D. MacMicking, associate professor of microbial pathogenesis at Yale School of Medicine and senior author the study. (more…)
