double helix – Shamskm: A site to exchange knowledge and solutions

SOFS Take to Water

By Guest PostJanuary 5, 2014Science2d honeycomb, aka chemistry, berkeley lab, chemical signals, DNA, double helix, emergence of nanotechnology, force, metal organic frameworks, mofs, molecule, non covalent bonds, saxs, sofs, solubility in water, supramolecular chemistry, supramolecular organic frameworks, van der waals, xin zhao, yi liu, zhan ting li

Researchers at Berkeley Lab’s Molecular Foundry Create First Soluble 2D Supramolecular Organic Frameworks

Supramolecular chemistry, aka chemistry beyond the molecule, in which molecules and molecular complexes are held together by non-covalent bonds, is just beginning to come into its own with the emergence of nanotechnology. Metal-organic frameworks (MOFs) are commanding much of the attention because of their appetite for greenhouse gases, but a new player has joined the field – supramolecular organic frameworks (SOFs). Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have unveiled the first two-dimensional SOFs that self-assemble in solution, an important breakthrough that holds implications for sensing and separation technologies, energy sciences, and, perhaps most importantly, biomimetics. (more…)

Researchers Find Gold Nanoparticles Capable of ‘Unzipping’ DNA

By Guest PostJune 23, 2012Scienceanatoli melechko, double helix, double stranded dna, electronics, gene therapy, gold nanoparticles, hydrophobic, justin railsback, nanoelectronic circuits, nanoparticles, organic molecules, timothy mcknight, unzipping dna, yaroslava yingling

New research from North Carolina State University finds that gold nanoparticles with a slight positive charge work collectively to unravel DNA’s double helix. This finding has ramifications for gene therapy research and the emerging field of DNA-based electronics.

“We began this work with the goal of improving methods of packaging genetic material for use in gene therapy,” says Dr. Anatoli Melechko, an associate professor of materials science and engineering at NC State and co-author of a paper describing the research. Gene therapy is an approach for addressing certain medical conditions by modifying the DNA in relevant cells. (more…)

UCLA Scientists Discover How Key Enzyme Involved in Aging, Cancer Assembles

By Guest PostJune 21, 2012Healthassembly of telomerase, chromosomal caps, degradation of dna, double helix, genetic code, la motif proteins, live forever, telomerase rna

UCLA biochemists have mapped the structure of a key protein–RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging. (more…)

New Molecule Has Potential to Help Treat Genetic Diseases and HIV

By Guest PostFebruary 13, 2012Scienceamy rhoden smith, austin, base molecule, brent iverson, cells, chromosome, DNA, dna sequence, double helix, garen holman, georgetown, hiv, kenneth johnson, legos, maha zewail foote, molecule, naphthalenetetracarboxylic diimide, ndi, protease inhibitors, sequence of genes, southwestern university, spiral staircase, university of texas, viral dna

AUSTIN, Texas — Chemists at The University of Texas at Austin have created a molecule that’s so good at tangling itself inside the double helix of a DNA sequence that it can stay there for up to 16 days before the DNA liberates itself, much longer than any other molecule reported.

It’s an important step along the path to someday creating drugs that can go after rogue DNA directly. Such drugs would be revolutionary in the treatment of genetic diseases, cancer or retroviruses such as HIV, which incorporate viral DNA directly into the body’s DNA. (more…)

DNA Caught Rock ‘n Rollin’

By Guest PostFebruary 6, 2011Sciencedna double helix, dna structural forms, double helix, hoogsteen base pair, molecule of life

ANN ARBOR, Mich.— DNA, that marvelous, twisty molecule of life, has an alter ego, research at the University of Michigan and the University of California, Irvine reveals. (more…)

Tag Archives: double helix

SOFS Take to Water

Researchers Find Gold Nanoparticles Capable of ‘Unzipping’ DNA

UCLA Scientists Discover How Key Enzyme Involved in Aging, Cancer Assembles

New Molecule Has Potential to Help Treat Genetic Diseases and HIV

DNA Caught Rock ‘n Rollin’