Tag Archives: lei zhang

Gleiche Hypothese, gleiche Daten – variable Ergebnisse?

Metastudie zeigt, wie Wissenschaft sich selbst kritisch hinterfragen und kontrollieren kann

Kritische Selbstreflexion im Wissenschaftsbetrieb ist unabdingbar – die derzeitige Corona-Krise bestätigt dies eindrücklich. In einem Experiment haben rund 200 internationale Forscher*innen unabhängig voneinander denselben Datensatz über Gehirnaktivität während einer Magnetresonanztomographie analysiert. Ziel war es abzuschätzen, wie variabel die Ergebnisse der bildgebenden Hirnforschung sein können. Zudem sollte überprüft werden, inwiefern sowohl die beteiligten als auch an den Auswertungen unbeteiligte Wissenschafter*innen die Ergebnisse vorhersagen konnten. (more…)

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China’s chance to reinvent itself environmentally

China’s 34-year-old Environmental Protection Law was created when it made sense for legislators in a developing country to trade environmental well-being for a boost to the gross domestic product.

Today, China wrestles with pollution that is leaving its citizens gasping for clean air, worried about water quality and concerned for the safety of the food grown there. In the current issue of Science, a team of researchers, including a Michigan State University sustainability expert, offers guidelines for revising the EPL to protect both humans and nature. (more…)

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Under the Electron Microscope – A 3-D Image of an Individual Protein

*The high resolution of Lawrence Berkeley National Laboratory’s Gang Ren*

When Gang Ren whirls the controls of his cryo-electron microscope, he compares it to fine-tuning the gearshift and brakes of a racing bicycle. But this machine at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) is a bit more complex. It costs nearly $1.5 million, operates at the frigid temperature of liquid nitrogen, and it is allowing scientists to see what no one has seen before.

At the Molecular Foundry, Berkeley Lab’s acclaimed nanotechnology research center, Ren has pushed his Zeiss Libra 120 Cryo-Tem microscope to resolutions never envisioned by its German manufacturers, producing detailed snapshots of individual molecules. Today, he and his colleague Lei Zhang are reporting the first 3-D images of an individual protein ever obtained with enough clarity to determine its structure. (more…)

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