Tag Archives: infectious disease

Breaking Dengue Fever

Like malaria, dengue fever is an infectious disease transmitted by mosquitoes. Unlike malaria, there is no vaccine for it. As many as 100 million people contract dengue each year, but MSU researcher Zhiyong Xi is working to change that.

Among the estimated 2.5 billion people at risk for dengue, more than 70 percent live in Asia Pacific countries, which spurred Xi to establish a collaborative research institute at Sun Yat-sen University in Guangzhou, China. (more…)

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UCLA Researchers Combat Global Disease with a Cell Phone, Google Maps and a Lot of Ingenuity

In the fight against emerging public health threats, early diagnosis of infectious diseases is crucial. And in poor and remote areas of the globe where conventional medical tools like microscopes and cytometers are unavailable, rapid diagnostic tests, or RDTs, are helping to make disease screening quicker and simpler. (more…)

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Nano-Sized Protein Clusters Address Major Challenge of Drug Delivery

AUSTIN, TX — A new form of proteins discovered by researchers at The University of Texas at Austin could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics: delivering drugs to patients safely, easily and more effectively.

The protein formulation strategy, discovered by chemical engineering faculty members and students in the Cockrell School of Engineering, is unprecedented and offers a new and universal approach to drug delivery — one that could revolutionize treatment of cancer, arthritis and infectious disease. (more…)

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Making Germs Glow: New Test Helps Save Lives and Cuts Costs

*Replacing conventional laboratory tests with a new DNA sequence-based technology to identify pathogens causing bloodstream infections dramatically lowered mortality and health-care costs, a clinical study conducted by an interdisciplinary UA research team found.*

Unlike conventional laboratory tests, a new technology called PNA-FISH is designed to rapidly identify bloodstream pathogens by their genetic code. Results are available within hours instead of days providing pharmacists and physicians with information they can use to rapidly customize antimicrobial treatment for patients with infections.

PNA-FISH is an abbreviation for “peptide nucleic acid fluorescence in situ hybridization.” Rapid reporting of PNA FISH results to pharmacists and physicians cut the mortality of ICU patients with enterococcus or streptococcus bloodstream infections by almost half and slashed mortality from yeast infections by 86 percent. In addition, the intervention resulted in healthcare cost reduction of almost $5 million per year. (more…)

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