Tag Archives: global gene expression

Genes and obesity: Fast food isn’t only culprit in expanding waistlines — DNA is also to blame

Researchers at UCLA say it’s not just what you eat that makes those pants tighter — it’s also genetics. In a new study, scientists discovered that body-fat responses to a typical fast-food diet are determined in large part by genetic factors, and they have identified several genes they say may control those responses.

The study is the first of its kind to detail metabolic responses to a high-fat, high-sugar diet in a large and diverse mouse population under defined environmental conditions, modeling closely what is likely to occur in human populations. The researchers found that the amount of food consumed contributed only modestly to the degree of obesity. (more…)

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Scientists Develop Technology Revolutionizing Single-Cell Studies

Researchers at the University of Hawaiʻi at Mānoa, in collaboration with scientists at the J. Craig Venter Institute, have made a significant breakthrough in developing a novel technology to investigate global gene-expression in a single bacterium. The team, led by Associate Professors Tung T. Hoang and Stuart P. Donachie, recently published a paper describing the technology in Genome Research (21:925-935), a premier international genome journal. UH Mānoa postdoctoral researcher Dr. Yun Kang, who performed this research in a Snyder Hall laboratory, contributed significantly and worked diligently to overcome the numerous technical challenges presented. (more…)

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