ANN ARBOR, Mich.— A technique that lets researchers monitor single cancer cells in real time as they float in liquid could help doctors study the breakaway tumor cells that cause metastasis. Metastasis is the process of the disease spreading through the body. (more…)
*Replacing conventional laboratory tests with a new DNA sequence-based technology to identify pathogens causing bloodstream infections dramatically lowered mortality and health-care costs, a clinical study conducted by an interdisciplinary UA research team found.*
Unlike conventional laboratory tests, a new technology called PNA-FISH is designed to rapidly identify bloodstream pathogens by their genetic code. Results are available within hours instead of days providing pharmacists and physicians with information they can use to rapidly customize antimicrobial treatment for patients with infections.
PNA-FISH is an abbreviation for “peptide nucleic acid fluorescence in situ hybridization.” Rapid reporting of PNA FISH results to pharmacists and physicians cut the mortality of ICU patients with enterococcus or streptococcus bloodstream infections by almost half and slashed mortality from yeast infections by 86 percent. In addition, the intervention resulted in healthcare cost reduction of almost $5 million per year. (more…)
*New map of the genetic code of endangered orangutans yields important new conservation tools and insights into evolution*
For the first time, scientists have mapped the genome–the genetic code–of orangutans. This new tool may be used to support efforts to maintain the genetic diversity of captive and wild orangutans. The new map of the orangutan genome may also be used to help improve our understanding of the evolution of primates, including humans.
Partially funded by the National Science Foundation, the orangutan study appears in the Jan. 27 issue of Nature. It was conducted by an international team of scientists led by Devin P. Locke of the Genome Center at Washington University. (more…)
