Tag Archives: embryonic stem cells

How a Silly Putty ingredient could advance stem cell therapies

ANN ARBOR — The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows.

The researchers coaxed human embryonic stem cells to turn into working spinal cord cells more efficiently by growing the cells on a soft, utrafine carpet made of a key ingredient in Silly Putty. Their study is published online at Nature Materials on April 13. (more…)

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Photoreceptor Transplant Restores Vision in Mice

Scientists from the UCL Institute of Ophthalmology have shown for the first time that transplanting light-sensitive photoreceptors into the eyes of visually impaired mice can restore their vision.

The research, published in Nature, suggests that transplanting photoreceptors – light-sensitive nerve cells that line the back of the eye – could form the basis of a new treatment to restore sight in people with degenerative eye diseases. (more…)

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Scientists Use Animal-Free Reagents to Create Clinical-Grade Neurons from Skin Cells

Using a specially designed facility, UCLA stem cell scientists have taken human skin cells, reprogrammed them into cells with the same unlimited property as embryonic stem cells, and then differentiated them into neurons while completely avoiding the use of animal-based reagents and feeder conditions throughout the process.

Generally, stem cells are grown using mouse “feeder” cells, which help the stem cells flourish and grow. But such animal-based products can lead to unwanted variations and contamination, and the cells must be thoroughly tested before they can be deemed safe for use in humans. (more…)

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