Tag Archives: behind the scenes

Drug-resistant lung cancer may have Achilles heel

Drugs introduced more than a decade ago that target mutations in a protein known as the epidermal growth factor receptor (EGFR) held the promise of personalized treatments for a common form of non-small cell lung cancer. But most patients quickly develop resistance to these drugs and are left with few or no treatment options, because it has been very difficult to design new drugs that act selectively upon the drug-resistant form.  (more…)

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