Tag Archives: bacterium

Smarter Toxins Help Crops Fight Resistant Pests

*A slight change in molecular structure introduced by genetic engineering gives crop-protecting proteins called Bt toxins a new edge in overcoming resistance of certain pests, a UA-led team of researchers reports in Nature Biotechnology.*

One of the most successful strategies in pest control is to endow crop plants with genes from the bacterium Bacillus thuringiensis, or Bt for short, which code for proteins that kill pests attempting to eat them.

But insect pests are evolving resistance to Bt toxins, which threatens the continued success of this approach. In the current issue of Nature Biotechnology, a research team led by UA Professor Bruce Tabashnik reports the discovery that a small modification of the toxins’ structure overcomes the defenses of some major pests that are resistant to the natural, unmodified Bt toxins. (more…)

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Close Up Look at a Microbial Vaccination Program

*Berkeley Lab Researchers Resolve Sub-nanometer Structure of Cascade, an Ally for Human Immune System*

A complex of proteins in the bacterium E.coli that plays a critical role in defending the microbe from viruses and other invaders has been discovered to have the shape of a seahorse by researchers with the U.S Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). This discovery holds far more implications for your own health than you might think.

In its never-ending battle to protect you from infections by bacteria, viruses, toxins and other invasive elements, your immune system has an important ally – many allies in fact. By the time you reach adulthood, some 90-percent of the cells in your body are microbial. These microbes – collectively known as the microbiome – play a critical role in preserving the health of their human host. (more…)

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A Bug Like a Russian Doll

*A former UA postdoctoral fellow has discovered amazing relationships between organisms: a bacterium living inside a bacterium living inside an insect. Evolving together, the organisms depend on each other for survival, and each contributes a subset of the enzymes needed in shared metabolic pathways.*

Sure, many bacteria cause disease, but most people don’t realize how beneficial they can be. The human gut, for example, brims with bacteria that play critical roles in everything from immune system development and extracting energy from food to providing necessary nutrients.

They get a nice comfy home living inside people, and in return they help us. It’s a symbiotic relationship. However, these beneficial partnerships are nothing compared to the complex relationships between bacteria and citrus mealybugs recently discovered by a team of biologists led by former UA researcher John McCutcheon, who recently took a position as an assistant professor at the University of Montana. (more…)

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Tuberculosis Protects Itself Against Toxic Agents Sent to Destroy It

ANN ARBOR, Mich.—Tuberculosis fights off the toxic agents, acidity and oxidants, that our immune system sends to destroy it, which is why the maddeningly drug-resistant bacterium can survive in harsh conditions in our bodies for essentially as long as its human host lives, new research shows. (more…)

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Bacteria Make Thrift a Habit

ANN ARBOR, Mich.— In these lean times, smart consumers refuse to pay a lot for throwaway items, but will shell out a little more for products that can be used again and again. The same is true of bacteria and other microbes, researchers at the University of Michigan have learned.

(more…)

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