Technology

Lack of Key Enzyme in the Metabolism of Folic Acid Leads to Birth Defects

AUSTIN, Texas — Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.

It has been known for several decades that folic acid supplementation dramatically reduces the incidence of neural tube defects, such as spina bifida and anencephaly, which are among the most common birth defects. In some populations, folic acid supplementation has decreased neural tube defects by as much as 70 percent. (more…)

Read More

Golden Algae: They Hunt, They Kill, They Cheat

Cheating is a behavior not limited to humans, animals and plants. Even microscopically small, single-celled algae do it, a team of UA researchers has discovered.

Humans do it, chimpanzees do it, cuckoos do it – cheating to score a free ride is a well-documented behavior by many animals, even plants. But microscopically small, single-celled algae? Yes, they do it too, biologists with the University of Arizona’s department of ecology and evolutionary biology have discovered. (more…)

Read More

Martian Crater May Once Have Held Groundwater-Fed Lake

PASADENA, Calif. — A NASA spacecraft is providing new evidence of a wet underground environment on Mars that adds to an increasingly complex picture of the Red Planet’s early evolution.

The new information comes from researchers analyzing spectrometer data from NASA’s Mars Reconnaissance Orbiter, which looked down on the floor of McLaughlin Crater. The Martian crater is 57 miles (92 kilometers) in diameter and 1.4 miles (2.2 kilometers) deep. McLaughlin’s depth apparently once allowed underground water, which otherwise would have stayed hidden, to flow into the crater’s interior. (more…)

Read More

Costly Breast Cancer Screenings Don’t Add up to Better Outcomes

Even though Medicare spends over $1 billion per year on breast cancer screenings such as a mammography, there is no evidence that higher spending benefits older women, researchers at Yale School of Medicine found in a study published Online First by JAMA Internal Medicine, a JAMA Network publication.

Led by Dr. Cary Gross, associate professor of internal medicine at Yale School of Medicine and director of the Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale, the study sought to provide a comprehensive understanding of breast cancer expenditures that incorporate the cost of screening and associated work-up, as well as treatment. They assessed overall national costs, as well as variation in costs across geographic regions. (more…)

Read More

Study Explains Skin’s Response to UVA Light

Researchers have strengthened their understanding of how skin cells called melanocytes sense ultraviolet light and act to protect themselves with melanin. In a new study, they report experiments showing that an ion channel well-known elsewhere in the body for its chemical sensitivity, plays a central role in this process. (more…)

Read More