Finding may lead to new target for treatment
In the past decade, scientists have identified a handful of genes connected with Parkinson’s disease. Now, a team of UCLA researchers has identified another gene involved in the neurological disorder. Their finding may provide a target for drugs that could one day prevent or even cure the debilitating illness. (more…)
For youth dealing with obesity who need extra help losing weight, experts suggest a multidisciplinary approach in which care is provided by several health specialists. However, the logistics of traveling to multiple appointments, even if just across town, can be a barrier to receiving care, especially for low-income families.
UCLA researchers who work with this patient population set up a pilot program using telehealth technology — a secure system that allowed patients to see and speak with their health care providers at UCLA over a computer from their local health clinic — to evaluate if such a system could be an effective strategy to help overcome these issues. (more…)
‘Deformability cytometry’ can closely analyze more than 1,000 cells per second
A team of researchers from UCLA and Harvard University have demonstrated a technique that, by measuring the physical properties of individual cells in body fluids, can diagnose cancer with a high degree of accuracy.
The technique, which uses a deformability cytometer to analyze individual cells, could reduce the need for more cumbersome diagnostic procedures and the associated costs, while improving accuracy over current methods. The initial clinical study, which analyzed pleural fluid samples from more than 100 patients, was published in the current issue of peer-reviewed journal Science Translational Medicine. (more…)
Specific area of the brain linked to anxiety disorders in youth
Anxiety disorders are common in children and adolescents, affecting up to 25 percent of the youth population. Anxiety causes distress and functional impairment and, if left untreated, can result in bad grades, problems at home and increased rates of psychiatric disorders in adulthood.
These risks constitute a significant public health burden, and they underscore the importance of continued efforts to understand the cause and course of the disorder. (more…)
UCLA researchers report that tiny amounts of a specific type of lipid in the small intestine may play a greater role than previously thought in generating the high cholesterol levels and inflammation that lead to clogged arteries.
The team also found they could reduce the negative effects of these lipids in mice by feeding the animals a new genetically engineered tomato being developed at UCLA that is designed to mimic HDL (“good”) cholesterol. (more…)
UCLA researchers have described a new form of irritable bowel syndrome that occurs after an acute bout of diverticulitis, a finding that may help lead to better management of symptoms and relief for patients.
The discovery of this new condition, called post-diverticulitis irritable bowel syndrome (PDV–IBS), validates the irritable bowel symptoms that many patients report long after suffering a bout of diverticulitis but that many physicians have waved off as being part of the original condition, said Dr. Brennan Spiegel, an associate professor of medicine at the David Geffen School of Medicine at UCLA and senior author of the research. (more…)
