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Making Blood-Sucking Deadly for Mosquitoes

By Guest PostJuly 17, 2011Scienceaedes aegypti, biochemical processes, blood feeding, blood meal, cellular process, coatomer protein 1, copi, copi system, dengue fever, dengue hemorrhagic fever, dengue viruses, digestive enzymes, egg production cycle, jun isoe, molecular process cells, mosquitoes, protein complex, proteins, rnai, roger miesfeld, secretion of enzymes, sub tropical, tablespoons of sugar, the university of arizona, toolbox, tropical regions of africa, vesicle transport, warm blooded animals

*Inhibiting a molecular process cells use to direct proteins to their proper destinations causes more than 90 percent of affected mosquitoes to die within 48 hours of blood feeding, a UA team of biochemists found.*

Mosquitoes die soon after a blood meal if certain protein components are experimentally disrupted, a team of biochemists at the University of Arizona has discovered.

The approach could be used as an additional strategy in the worldwide effort to curb mosquito-borne diseases like dengue fever, yellow fever and malaria. (more…)

U of T researcher discovers key protein involved in DNA repair

By Guest PostAugust 22, 2010Health, Scienceanne‐claude gingras, cancer, cancer development, cells, daniel durocher, dann, dna repair, frank sicheri, genetic material, mount sinai hospital, mutations, otub1, protein, riddle syndrome, rna interference, rnai, samuel lunenfeld research institute, thomas kierans research chair

*Discovery gives insight into the way cells protect their own genetic material*

In a groundbreaking study, U of T researchers including Professors Daniel Durocher, Anne‐Claude Gingras and Frank Sicheri have uncovered a protein called OTUB1 that blocks DNA damage in the cell—a discovery that may lead to the development of strategies to improve some cancer therapies.

(more…)

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Making Blood-Sucking Deadly for Mosquitoes

U of T researcher discovers key protein involved in DNA repair