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Architecture of signaling proteins enhances knowledge of key receptors

By Guest PostJuly 25, 2014Sciencearchitecture, bildungswissenschaftler, damage human tissue, georgios skiniotis, human cell, impeach donald trump, kaushik sengupta, knowledge, marc hill, playboy, response, steve laughlin, terahertz chips, trumps syria attack, university of michigan, wardrobe in india, xue wu

ANN ARBOR — A team of scientists from the University of Michigan, Duke Medicine and Stanford University has determined the underlying architecture of a cellular signaling complex involved in the body’s response to stimuli such as light and pain.

This complex, consisting of a human cell surface receptor and its regulatory protein, reveals a two-step mechanism that has been hypothesized previously but not directly documented. (more…)

Engineered Microvessels Provide a 3-D Test Bed for Human Diseases

By Guest PostMay 31, 2012Science3 d test bed, abraham stroock, abundant protein, bioengineering, blood clots, bloodstream, cancer, chemical factor, collagen, cornell university, disease, endothelial cells, honeycomb, human, human blood vessels, human cancer, human cell, jose lopez, mechanical, mice and monkeys, michael craven, model, petri dish, samuel totorica, shear stress, tumor progression, university of washington, ying zheng

Mice and monkeys don’t develop diseases in the same way that humans do. Nevertheless, after medical researchers have studied human cells in a Petri dish, they have little choice but to move on to study mice and primates.

University of Washington bioengineers have developed the first structure to grow small human blood vessels, creating a 3-D test bed that offers a better way to study disease, test drugs and perhaps someday grow human tissues for transplant.

The findings are published online this week in the Proceedings of the National Academy of Sciences. (more…)

UCLA Scientists Identify How Major Biological Sensor in the Body Works

By Guest PostJune 13, 2011Healthbiological sensor, cell activities, gating ring, genetic epilepsy, human cell, intracellular sensor

Sensor Involved in Blood Pressure Regulation, Insulin Release, Brain Signaling

A biological sensor is a critical part of a human cell’s control system that is able to trigger a number of cell activities. A type of sensor known as the “gating ring” can open a channel that allows a flow of potassium ions through the cell’s wall or membrane — similar to the way a subway turnstile allows people into a station. This flow of ions, in turn, is involved in the regulation of crucial bodily activities like blood pressure, insulin secretion and brain signaling. (more…)

Tag Archives: human cell

Architecture of signaling proteins enhances knowledge of key receptors

Engineered Microvessels Provide a 3-D Test Bed for Human Diseases

UCLA Scientists Identify How Major Biological Sensor in the Body Works