Scientists used genetic sequencing to discover that the vaccine used in the RV144 HIV vaccine trial, involving 16,000 men and women in Thailand, did offer some protection against certain HIV viruses. The results were published Sept. 10 in the online edition of Nature.(more…)
For the first time, the U.S. Food and Drug Administration is considering approving a drug that helps prevent someone from acquiring HIV. It’s called Truvada, and has been approved for use since 2004 to treat infected people.
Now it has been shown to protect healthy people who are exposed to HIV. The UW’s International Clinical Research Center, within the Department of Global Health, played a key role in examining the drug’s effectiveness for HIV prevention.
Researchers Connie Celum and Jared Baeten led a study, published this week in the New England Journal of Medicine, of pre-exposure prophylaxis among heterosexual couples in Kenya and Uganda. One partner had HIV (and was not yet eligible for HIV treatment) and the other partner did not have HIV. Uninfected partners were given either Truvada or Tenofovir (both antiretroviral drugs) or a placebo. (more…)