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To Be A Scientist

By Guest PostFebruary 24, 2012Scienceaids, aids drug, alzheimer, anti aging, anti cancer compounds, anti tumor agents, bob vince, carbovirs, cdd, center for drug design, chemical formulas, childhood home, detection, DNA, eugene mccarthy, explosive, genetic material, hall of fame, hiv, nobel laureate, norman borlaug, patent, precursor, quality of life, scholars walk, scientist, senator, t cells, tc campus, treatment, wall of discovery, walter mondale, ziagen

*How Bob Vince changed the world*

Where does it begin, the act of becoming a scientist? Perhaps with a bowling ball, its finger holes packed with explosives, which when detonated, launch the ball into the air, cracking the otherwise pristine concrete walkway of your childhood home in four places, much to the consternation of your father. Or maybe with an explosion of homemade rocket fuel in your basement chemistry lab that scares your mother half to death. And all this before the troublesome teen years.

Bob Vince can’t be sure where his becoming a scientist began. But where it led changed the world. (more…)

Yale Researchers Discover Promising Anti-HIV Agents

By Guest PostNovember 23, 2011Health, Sciencebristol myers squibb, chemical compounds, d4t, DNA, effective hiv treatments, festinavir, function of an enzyme, genetic material, hiv 1 reverse transcriptase, hiv and human t cells, hiv drugs, hiv replication, human t cells, infection of human cells, jlj494, karen s anderson, less toxic aids drugs, mariela bollini, non nucleoside reverse transcriptase inhibitors, prevent hiv, prophylactic anti hiv treatment, reverse transcriptase inhibitor, tai shun lin, toxicity, vinay v thakur, wild type, wild type hiv, william h prusoff, william l jorgensen, yung chi tommy cheng, zerit

Researchers at Yale University have discovered new chemical compounds that prevent HIV from replicating in human T-cells. These compounds could result in new, highly effective HIV treatments that are 10 to 2000 times more potent than HIV drugs now on the market.

“The current compounds or slight variants could become drugs,” said Professor William L. Jorgensen, one of two principal investigators behind the research. The other is Karen S. Anderson, a pharmacology professor at Yale School of Medicine. They reported their results online Nov. 15 in the Journal of Medicinal Chemistry. (more…)

U of T researcher discovers key protein involved in DNA repair

By Guest PostAugust 22, 2010Health, Scienceanne‐claude gingras, cancer, cancer development, cells, daniel durocher, dann, dna repair, frank sicheri, genetic material, mount sinai hospital, mutations, otub1, protein, riddle syndrome, rna interference, rnai, samuel lunenfeld research institute, thomas kierans research chair

*Discovery gives insight into the way cells protect their own genetic material*

In a groundbreaking study, U of T researchers including Professors Daniel Durocher, Anne‐Claude Gingras and Frank Sicheri have uncovered a protein called OTUB1 that blocks DNA damage in the cell—a discovery that may lead to the development of strategies to improve some cancer therapies.

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Tag Archives: genetic material

To Be A Scientist

Yale Researchers Discover Promising Anti-HIV Agents

U of T researcher discovers key protein involved in DNA repair