Tau-tally Microtubular!
Structural model of physiological tau-microtubule interactions sheds light on neurological diseases that correlate with their disruption
Researchers at Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California, Berkeley have combined cutting-edge cryo-electron microscopy (cryo-EM) with computational molecular modeling to produce a near-atomic-resolution model of the interaction between microtubules – crucial components of eukaryotic cell ultrastructure – and microtubule-associated proteins called tau. (more…)