Tag Archives: web based program

Web app prompts important sexual health testing

ANN ARBOR — A personalized web app designed to encourage young men at risk for sexually transmitted diseases to go for testing has proven successful in a small trial conducted in Southeast Michigan.

Researchers at the University of Michigan’s Center for Sexuality & Health Disparities developed the web-based program called “Get Connected” to encourage young men who have sex with men to get tested for HIV and other sexually transmitted infections, including chlamydia, gonorrhea and syphilis. (more…)

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Will a Genetic Mutation Cause Trouble? Ask Spliceman

New, free Web-based software described in the journal Bioinformatics analyzes DNA sequences to determine if mutations are likely to cause errors in splicing of messenger RNA. When gene splicing goes awry, a wide variety of diseases can result.

PROVIDENCE, R.I. [Brown University] — In a brief paper in the journal Bioinformatics, Brown University researchers describe a new, freely available Web-based program called Spliceman for predicting whether genetic mutations are likely to disrupt the splicing of messenger RNA, potentially leading to disease.

“Spliceman takes a set of DNA sequences with point mutations and computes how likely these single nucleotide variants alter splicing phenotypes,” write co-authors Kian Huat Lim, a graduate student, and William Fairbrother, assistant professor of biology, in an “application note” published in advance online Feb. 10. It will appear in print in April. (more…)

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