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Study in Mice Raises Question: Could PTSD Involve Immune Cell Response to Stress?

After chronic stress, primed immune cells in spleen lead to excessive reaction to later event

COLUMBUS, Ohio – Chronic stress that produces inflammation and anxiety in mice appears to prime their immune systems for a prolonged fight, causing the animals to have an excessive reaction to a single acute stressor weeks later, new research suggests.

After the mice recovered from the effects of chronic stress, a single stressful event 24 days later quickly returned them to a chronically stressed state in biological and behavioral terms. Mice that had not experienced the chronic stress were unaffected by the single acute stressor. (more…)

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