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Mutation Breaks HIV’s Resistance to Drugs, Says MU Researcher

Doctors can improve treatment programs using this knowledge

COLUMBIA, Mo. – The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including University of Missouri scientists, found that one of those mutations, called 172K, made certain forms of the virus more susceptible to treatment. Soon, doctors will be able to use this knowledge to improve the drug regimen they prescribe to HIV-infected individuals.

“The 172K polymorphism makes certain forms of HIV less resistant to drugs,” said Stefan Sarafianos, corresponding author of the study and a researcher at MU’s Bond Life Sciences Center. “172K doesn’t affect the virus’ normal activities. In some varieties of HIV that have developed resistance to drugs, when the 172K mutation is present, resistance to two classes of anti-HIV drugs is suppressed. We estimate up to 3 percent of HIV strains carry the 172K polymorphism.” (more…)

World’s Most Powerful Digital Camera Begins Hunt for Dark Energy

Science

Eight billion years ago, rays of light from distant galaxies began their long journey to Earth. That ancient starlight has now found its way to a mountaintop in Chile, where the newly constructed Dark Energy Camera, the most powerful sky-mapping machine ever created, has captured and recorded it for the first time. (more…)

New Study Analyzes Why People Are Resistant to Correcting Misinformation, Offers Solutions

Science

ANN ARBOR, Mich.— Childhood vaccines do not cause autism. President Obama was born in the United States. Global warming is confirmed by science. And yet, many people believe claims to the contrary.

In a study appearing in the current issue of Psychological Science in the Public Interest, researchers from the University of Michigan, University of Western Australia and University of Queensland examined factors that cause people to resist correcting misinformation.

Misinformation can originate from rumors but also fiction, government and politicians, and organizations, the researchers say. (more…)

IBM and Broadridge Study Reveals Financial Markets Firms Challenged to Deliver Innovation and Efficiency

Technology

Only 1 in 5 firms excels at supporting new regulation and responding rapidly to client demands

Leading firms are rethinking their operations, forming external partnerships

NEW YORK, N.Y. – 21 Sep 2012: A new report released by IBM in collaboration with Broadridge Financial Solutions, Inc. reveals that increasing regulatory pressures and shifting customer demands are forcing financial markets firms to transform how they operate. Forward-thinking firms are breaking away from the industry’s long-held “not invented here” approach to managing operations to create a more open, agile and customer-focused model that expands the traditional boundaries of collaboration with external partners. (more…)

Berkeley Lab Scientists Create First 3-D Model of a Protein Critical to Embryo Development

Science

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein, PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved therapeutic drugs. (more…)

IBM X-Force 2012 Mid-Year Trend and Risk Report: Rising Attacks Focus on Browsers and Social Media Networks

Technology

New global security operations center in Wroclaw, Poland helps clients stay ahead of threats

ARMONK, N.Y. – 20 Sep 2012: IBM today released the results of its X-Force 2012 Mid-Year Trend and Risk Report, which shows a sharp increase in browser-related exploits, renewed concerns around social media password security, and continued challenges in mobile devices and corporate “bring your own device” (BYOD) programs.

To further protect its clients from emerging threats like those reported in the IBM X-Force Mid-Year Trend and Risk Report, IBM is today announcing the opening of a security operations center in Wroclaw, Poland. This newest IBM Security Operations Center is the 10^th worldwide facility to help clients proactively manage these threats, including real-time analysis and early warning notification of security events. Data for the bi-annual X-Force report comes from IBM’s security operations centers which monitor more than 15 billion security events a day on behalf of approximately 4,000 clients in more than 130 countries. (more…)

Evolution is as Complicated as 1-2-3

Science

EAST LANSING, Mich. — A team of researchers at Michigan State University has documented the step-by-step process in which organisms evolve new functions. (more…)

Shrinking Snow Depth on Arctic Sea Ice Threatens Ringed Seal Habitat

Environment

As sea ice in the Arctic continues to shrink during this century, more than two thirds of the area with sufficient snow cover for ringed seals to reproduce also will disappear, challenging their survival, scientists report in a new study.

The ringed seal, currently under consideration for threatened species listing, builds caves to rear its young in snow drifts on sea ice. Snow depths must be on average at least 20 centimeters, or 8 inches, to enable drifts deep enough to support the caves. (more…)