EAST LANSING, Mich. — Two teams of Michigan State University researchers – one working at a medieval burial site in Albania, the other at a DNA lab in East Lansing – have shown how modern science can unlock the mysteries of the past. (more…)
*U of T, U.K. study focused on Avastin*
Treating ovarian cancer with the drug bevacizumab (“Avastin”) delays the disease and may also improve survival, according to an international clinical trial co-led by Drs. Amit Oza of the University of Toronto and Princess Margaret Hospital (PMH) and Timothy Perren of St James’s Institute of Oncology, Leeds, U.K.
The findings, published on Dec. 28 in the New England Journal of Medicine, report that the drug halted the cancer’s return for two months overall. However, for women with the highest risk disease, the delay was five to six months and in this group, the findings also indicate a strong trend to improved overall survival, which is being analysed until 2013. (more…)
*As we begin the New Year, a look at some of the stories of futuristic scenarios brought to life in 2011, plus developments that promise dramatic improvements in the near future.*
REDMOND, Wash. – Jan. 3, 2012 – From revolutionizing the way we interact with computers to developing tools to speed development of cures for crippling diseases, 2011 was a year of forward-thinking breakthroughs at Microsoft. See some of the innovations introduced in 2011 and how Microsoft is working to take new technologies from the lab to the living room. (more…)
For decades, science has suggested that when people make decisions, they tend to ignore logic and go with the gut. But Wim De Neys, a psychological scientist at the University of Toulouse in France, has a new suggestion: Maybe thinking about logic is also intuitive. He writes about this idea in the January issue of Perspectives on Psychological Science, a journal of the Association for Psychological Science. (more…)
*Proprotein convertases are enzymes that activate many essential proteins, but they are also implicated in many processes that cause disease. In a research review in the New England Journal of Medicine, Andrew Artenstein and Steven Opal argue that proprotein convertases are potentially rich targets for developing therapies.*
Most people have never heard of proprotein convertases, but the enzymes activate many proteins that are essential for life. Unfortunately, their fundamental role puts them in the middle of many processes that cause disease – not just cancer or athlerosclerosis, but both of those and Alzheimer’s and anthrax and the flu and an amazing variety of other maladies.
In a research review article appearing Dec. 29 in the New England Journal of Medicine, Andrew Artenstein, physician-in-chief in the Department of Medicine at Memorial Hospital, and Steven Opal, chief of infectious diseases at Memorial Hospital, argue that proprotein convertases (PCs) are potentially rich targets for developing therapies. Artenstein, who with Opal is on the faculty of the Warren Alpert School of Medicine, explained PCs to David Orenstein. (more…)
Scientific discoveries come through many different means. Breakthroughs can result from purposefully-executed research projects that are perhaps punctuated with unexpected flashes of insight. In rare cases, discoveries occur through a chain of highly improbable, very lucky, occurrences. (more…)
*Climate changes profoundly influenced the rise and fall of six distinct, successive waves of mammal species diversity in North America over the last 65 million years, shows a novel statistical analysis led by Brown University evolutionary biologists. Warming and cooling periods, in two cases confounded by species migrations, marked the transition from one dominant grouping to the next.*
PROVIDENCE, R.I. [Brown University] — History often seems to happen in waves — fashion and musical tastes turn over every decade and empires give way to new ones over centuries. A similar pattern characterizes the last 65 million years of natural history in North America, where a novel quantitative analysis has identified six distinct, consecutive waves of mammal species diversity or “evolutionary faunas.” What force of history determined the destiny of these groupings? The numbers say it was typically climate change.
“Although we’ve always known in a general way that mammals respond to climatic change over time, there has been controversy as to whether this can be demonstrated in a quantitative fashion,” said Christine Janis, professor of evolutionary biology at Brown University. “We show that the rise and fall of these faunas is indeed correlated with climatic change — the rise or fall of global paleotemperatures — and also influenced by other more local perturbations such as immigration events.” (more…)
COLUMBUS, Ohio – New research challenges the conventional thinking that young children use language just as adults do to help classify and understand objects in the world around them.
In a new study involving 4- to 5-year-old children, researchers found that the labels adults use to classify items – words like “dog” or “pencil” – don’t have the same ability to influence the thinking of children. (more…)
