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Understanding Angelman syndrome: Study in Mice Yields Angelman Advance

By Guest PostFebruary 25, 2013Scienceangelman mice, angelman syndrome, arc, bdnf, ben philpot, brain, brain derived, brown university, clinical therapy, cn2097, cong cao, crystal yu, dartmouth college, dennis goebel, development of synapses, electrophysiological tests, flaws in gene, gene defect, growth factor, hippocampal tissue, hippocampus, john marshall, learning, long-term potentiation, ltp, mark spaller, memory, memory function, mengia rioult pedotti, negative effects, neural functions, neurological processes, neurotrophic factor, north Carolina, paolo migani, peptide like compound, protein, psd 95, study in mice, synaptic protein, ube3a, understanding angelman syndrome, university, wayne state university

In the journal PLoS Biology, a team of scientists reports experiments showing how the gene defect of Angelman syndrome disrupts neurological processes that may be needed for memory and learning. In tests in mice, the team showed that a novel compound could restore the healthy processes.

PROVIDENCE, R.I. [Brown University] — In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems. With the new understanding, the team demonstrated how a synthesized, peptide-like compound called CN2097 works to restore neural functions impaired by the disease. (more…)

Get off my lawn: Song Sparrows Escalate Territorial Threats

By Guest PostFebruary 17, 2013Naturebehavior, brain mechanism, caglar akcay, communication system, cornell university, discovery park, distinctive ways, early warning signal, elizabeth campbell, flipping the bird, hierarchical warning scheme, human language, learn language, learning, male song sparrow, mari tom, melospiza melodia, michael beecher, pattern of signaling, people, seattle, song matching, territorial song sparrows, territory, threatening signals, trespassing rivals, university of washington, wing waving

Territorial song sparrows use increasingly threatening signals to ward off trespassing rivals. First an early warning that matches the intruder’s song, then wing waving – a bird’s version of “flipping the bird” – as the dispute heats up, and finally, if all other signals have failed, attack.

This hierarchical warning scheme, discovered by researchers at the University of Washington, adds nuance to a communication system that has been long-used as a model to study how people use and learn language (more…)

How Beliefs Shape Effort and Learning

By Guest PostApril 24, 2011Sciencebagasi, bridgid finn, columbia university, daniel c. molden, david b. miele, entity theorists, incremental theorists, indonesian, intelligence, learning, level of intelligence, luggage, motivation to learn, pembalut bandage, police, polisi, theories

If it was easy to learn, it will be easy to remember. Psychological scientists have maintained that nearly everyone uses this simple rule to assess their own learning.

Now a study published in an upcoming issue Psychological Science, a journal of the Association for Psychological Science, suggests otherwise: “Individuals with different theories about the nature of intelligence tend to evaluate their learning in different ways,” says David B. Miele of Columbia University, who conducted the study with Bridgid Finn of Washington University in St. Louis and Daniel C. Molden of Northwestern University. (more…)

Tag Archives: learning

Understanding Angelman syndrome: Study in Mice Yields Angelman Advance

Get off my lawn: Song Sparrows Escalate Territorial Threats

How Beliefs Shape Effort and Learning