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How a Silly Putty ingredient could advance stem cell therapies

By Guest PostApril 23, 2014Scienceals, alzheimer, amyotrophic lateral sclerosis, canadian ploye, disease, embryonic stem cells, farish jenkins, human, ingredient, jianping fu, lou gehrig, malaysian lempeng kelapa, rob eagle, silly putty, stem cell therapies, university of michigan, wie, yann bouremel

ANN ARBOR — The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows.

The researchers coaxed human embryonic stem cells to turn into working spinal cord cells more efficiently by growing the cells on a soft, utrafine carpet made of a key ingredient in Silly Putty. Their study is published online at Nature Materials on April 13. (more…)

Capturing Circulating Cancer Cells Could Provide Insights into How Disease Spreads

By Guest PostDecember 13, 2012Healthaggressive cancer cells, antibody, blood tests, bloodstream, breast cancer, cancer cells, cancer metastasis, cancer stem, cellsearch system, circulating tumor cells, coated magnetic beads, disease, distant tissues, glass plate, glass plates, jianping fu, metastatic process, michigan, nanoscale, nanoscale resolution, Nature, normal blood cells, patient, physical behaviour, progenitor cells, proteins, sofia merajver, solid tumors, university, weiqiang chen

ANN ARBOR — A glass plate with a nanoscale roughness could be a simple way for scientists to capture and study the circulating tumor cells that carry cancer around the body through the bloodstream.

Engineering and medical researchers at the University of Michigan have devised such a set-up, which they say takes advantage of cancer cells’ stronger drive to settle and bind compared with normal blood cells. (more…)

New Insights into How Stem Cells Determine What Tissue to Become

By Guest PostAugust 1, 20101 commentSciencechristopher chen, immunofluorescence image, jianping fu, matrix, mesenchymal stem cell, microposts, regenerative therapies, silly putty, stem cells

ANN ARBOR, Mich.—Within 24 hours of culturing adult human stem cells on a new type of matrix, University of Michigan researchers were able to make predictions about how the cells would differentiate, or what type of tissue they would become. Their results are published in the Aug. 1 edition of Nature Methods.

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How a Silly Putty ingredient could advance stem cell therapies

Capturing Circulating Cancer Cells Could Provide Insights into How Disease Spreads

New Insights into How Stem Cells Determine What Tissue to Become