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Stir no more: UW scientists show that draining speeds up bioassays

For many research scientists, idle time has long been an unwelcome feature of the discovery process. Advances in cellular biology have yielded popular and powerful tools to detect cellular proteins and DNA — largely by exploiting the unique and intricate interactions between these microscopic molecules. Scientists use these tools to advance research and diagnose diseases. But these come at a cost in time — from hours to days — before they yield accurate answers. (more…)

New Information on the Waste-Disposal Units of Living Cells

By Guest PostJanuary 15, 2012Scienceandreas martin, base, berkeley lab, biochemical processes, cellular proteins, charlene bashore, degradation, degrade, diseases, dna repair, eric estrin, eva nogales, gabriel lander, heterologous expression system, human cell, immune defense system, irreversible, kiss of death, lid, living cells, mary matyskiela, non atpase proteins, polypeptide, proteasome machinery, proteasome regulatory particle, proteasomes, protein functions, protein machines, regulatory particle, subnanometer scale, transcription, treatment of cancer, ubiquitin, university of california, waste disposal, yeast

*Berkeley Researchers Provide Detailed Look at Proteasome’s Regulatory Particle*

Important new information on one of the most critical protein machines in living cells has been reported by a team of researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley. The researchers have provided the most detailed look ever at the “regulatory particle” used by the protein machines known as proteasomes to identify and degrade proteins that have been marked for destruction. The activities controlled by this regulatory particle are critical to the quality control of cellular proteins, as well as a broad range of vital biochemical processes, including transcription, DNA repair and the immune defense system. (more…)

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Stir no more: UW scientists show that draining speeds up bioassays

New Information on the Waste-Disposal Units of Living Cells