Replacing the Blue Bloods
Liquid crystal droplets could replace horseshoe crab blood in common endotoxin test
The Food and Drug Administration requires every drug they certify to be tested for certain poisons that damage patient health. The current gold standard for this is the limulus amoebocyte lysate (LAL) assay that involves using the blood of horseshoe crabs, which strangely enough is blue, to test for endotoxin, a substance commonly associated with many symptoms caused by bacterial infections. (more…)