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Replacing the Blue Bloods

By Guest PostMay 24, 2011Sciencebacterial endotoxin, bacterial infections, biological nature, endotoxin, endotoxin contamination, horseshoe crabs, lal, limulus amoebocyte lysate, liquid crystals, mary galvin, national science foundation, nick abbott, non lethal method, ordering, poisons, university of wisconsin

*Liquid crystal droplets could replace horseshoe crab blood in common endotoxin test*

The Food and Drug Administration requires every drug they certify to be tested for certain poisons that damage patient health. The current gold standard for this is the limulus amoebocyte lysate (LAL) assay that involves using the blood of horseshoe crabs, which strangely enough is blue, to test for endotoxin, a substance commonly associated with many symptoms caused by bacterial infections.

But researchers at the Department of Chemical and Biological Engineering at the University of Wisconsin-Madison have found what may be a more effective way to test for endotoxin that involves liquid crystals, the same material used to make some flat screen computer monitors and televisions. (more…)

Unexpected Exoskeleton Remnants Found in Paleozoic Fossils

Washington, D.C.— Surprising new research shows that, contrary to conventional belief, remains of chitin-protein complex—structural materials containing protein and polysaccharide—are present in abundance in fossils of arthropods from the Paleozoic era. Previously the oldest molecular signature of chitin-protein complex was discovered in 25 million year old Cenozoic fossils and remnants of structural protein have also been discovered in 80 million-year-old Mesozoic fossils. Carnegie’s George Cody and an international team of scientists discovered relicts of protein-chitin complex in fossils of arthropods from the Paleozoic era. Their findings, published online by Geology, could have major implications for our understanding of the organic fossil record. (more…)

Tag Archives: horseshoe crabs

Replacing the Blue Bloods

Unexpected Exoskeleton Remnants Found in Paleozoic Fossils