Blog Post Image: Diabolical duo: Known breast cancer gene needs a partner to initiate and spread tumors

A team led by researchers at Princeton University has found that a gene known as Metadherin, or MTDH, promotes the survival of tumor-initiating cells via the interaction with a second molecule called SND1. Mammary tissue was taken from mice (stained red for visualization) that were genetically engineered to develop breast cancer in the presence (left) or absence (right) of MTDH. The dark-pink, cloud-like structures indicate the initiation of mammary tumors, which were largely suppressed by loss of the MTDH gene. (Image courtesy of Yibin Kang, Department of Molecular Biology)

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