Usually you do it from the View tab > in the Show/Hide group > uncheck the Gridlines option.
In the older versions like Excel 2003 or earlier: Go to Tools > Options > here under View tab > uncheck the Gridlines option > click OK.
So your gridlines will disappear from this

to this

keyboard shortcut to hide Excel Gridlines
However, there is a useful keyboard shortcut for Excel lovers to hide the gridlines:
Just use Alt + WVG – grids disappear

Do it again Alt + WVG – grids reappear!!
Have fun
